产品
编 号:F171811
分子式:C16H14N2O4
分子量:298.29
产品类型
结构图
CAS No: 147591-46-6
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产品详情
生物活性:
ID-8 is an inhibitor of dual-specificity tyrosine phosphorylation-regulated kinase (DYRK). ID-8 sustains embryonic stem cell (ESC) self-renewal and pluripotency. ID-8 enhances Wnt-mediated hESC survival and proliferation via inhibition of DYRKs.
体外研究:
ID-8 (0.1-10 μM) increases human embryonic stem cell (hESC) survival.ID-8 (10 μM) stimulates ESCs proliferation in serum-free media for more than 1 month.