产品
编 号：F186690
分子式：C35H36N4O5
分子量：592.68
分子式：C35H36N4O5
分子量：592.68
产品类型
规格
价格
是否有货
1mg
询价
询价
5mg
询价
询价
10mg
询价
询价
结构图
CAS No: 15664-29-6
产品详情
生物活性：
Pheophorbide A is an intermediate product in the chlorophyll degradation pathway. Pheophorbide A can be used as a photosensitizer. Pheophorbide A is a lymphatic vascular activator. Pheophorbide A has antitumor activity. Pheophorbide A can be used for human lymphatic vascular insufficiencies research.
体内研究：
Pheophorbide A 光动力疗法 (Pa-PDT) （10 mg/kg（静脉注射）或 30 mg/kg（腹腔注射））可显著抑制皮下注射 AT-84 细胞的 C3H 小鼠模型中的肿瘤生长。Animal Model:Male immunocompetent C3H mouse (six-week-old, inoculated subcutaneously with AT-84 cells)
Dosage:10 mg/kg intravenous (i.v.) or a 30 mg/kg intraperitoneal (i.p.) injection
Administration:IV or IP; after 24 h, PDT was performed
Result:Pa-PDT, especially i.v. Pa-PDT, significantly inhibited tumor growth up to 70%, while the i.p. Pa-PDT-induced inhibition was up to 43.4% relative to the control group at the end of period.
体外研究：
Pheophorbide A (10 μM) 可促进淋巴内皮细胞 (LEC) 萌芽、增殖和管形成。Pheophorbide A 介导的光动力疗法 (Pa-PDT) 以剂量依赖性方式抑制 Hep3B 上的细胞生长，IC50 为 1.5 μM。光激活后 Pheophorbide A (2 μM, 24 h) 可诱导 Hep3B 细胞凋亡。
Pheophorbide A is an intermediate product in the chlorophyll degradation pathway. Pheophorbide A can be used as a photosensitizer. Pheophorbide A is a lymphatic vascular activator. Pheophorbide A has antitumor activity. Pheophorbide A can be used for human lymphatic vascular insufficiencies research.
体内研究：
Pheophorbide A 光动力疗法 (Pa-PDT) （10 mg/kg（静脉注射）或 30 mg/kg（腹腔注射））可显著抑制皮下注射 AT-84 细胞的 C3H 小鼠模型中的肿瘤生长。Animal Model:Male immunocompetent C3H mouse (six-week-old, inoculated subcutaneously with AT-84 cells)
Dosage:10 mg/kg intravenous (i.v.) or a 30 mg/kg intraperitoneal (i.p.) injection
Administration:IV or IP; after 24 h, PDT was performed
Result:Pa-PDT, especially i.v. Pa-PDT, significantly inhibited tumor growth up to 70%, while the i.p. Pa-PDT-induced inhibition was up to 43.4% relative to the control group at the end of period.
体外研究：
Pheophorbide A (10 μM) 可促进淋巴内皮细胞 (LEC) 萌芽、增殖和管形成。Pheophorbide A 介导的光动力疗法 (Pa-PDT) 以剂量依赖性方式抑制 Hep3B 上的细胞生长，IC50 为 1.5 μM。光激活后 Pheophorbide A (2 μM, 24 h) 可诱导 Hep3B 细胞凋亡。
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