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编 号:F198844
分子式:C8H16N2O2
分子量:172.22
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生物活性:
NOS-IN-1 is a potent and orally active NO synthase (NOS) isoforms inhibitor with IC50s of 0.1 μM, 1.1 μM, and 0.2 μM for human iNOS (hiNOS), heNOS and hnNOS, respectively.

体内研究:
Following oral administration, NOS-IN-1 (compound 3; 10 mg/kg) decreases serum nitrite/nitrate levels in an in vivo rat endotoxin assay.
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