产品
编 号:F203551
分子式:C22H27N3O3S
分子量:413.53
产品类型
结构图
CAS No: 1700637-55-3
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产品详情
生物活性:
CD38 inhibitor 1 (compound 78c) is a potent CD38 inhibitor with IC50s of 7.3 nM and 1.9 nM for hCD38 and mouse CD38.
体内研究:
CD38 inhibitor (30 mg/kg; oral administration; 2 and 6 hours) significantly elevates NAD levels in liver and muscle.Animal Model:Diet induced obese (DIO) C57Bl6 mice
Dosage:30 mg/kg
Administration:Orally once
Result:NAD levels were significantly increased at both the 2 and 6 h time points in liver and muscle.