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编 号:F203551
分子式:C22H27N3O3S
分子量:413.53
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10mM*1mL in DMSO
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1mg
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5mg
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10mg
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25mg
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50mg
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生物活性:
CD38 inhibitor 1 (compound 78c) is a potent CD38 inhibitor with IC50s of 7.3 nM and 1.9 nM for hCD38 and mouse CD38.

体内研究:
CD38 inhibitor (30 mg/kg; oral administration; 2 and 6 hours) significantly elevates NAD levels in liver and muscle.Animal Model:Diet induced obese (DIO) C57Bl6 mice
Dosage:30 mg/kg
Administration:Orally once
Result:NAD levels were significantly increased at both the 2 and 6 h time points in liver and muscle.
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