产品
编 号：F206442
分子式：H6O9Si3.2Na.Zr
分子量：371.5
分子式：H6O9Si3.2Na.Zr
分子量：371.5
产品类型
规格
价格
是否有货
5mg
询价
询价
10mg
询价
询价
25mg
询价
询价
50mg
询价
询价
100mg
询价
询价
结构图
CAS No: 17141-74-1
产品详情
生物活性：
Sodium zirconium cyclosilicate is an orally administered, non-absorbed, novel, inorganic microporous zirconium silicate compound, is a highly selective cation exchanger that selectively removes excess K+ in vivo. Sodium zirconium cyclosilicate can be used in research of chronic kidney disease (CKD).
体内研究：
Sodium zirconium cyclosilicate (ZS-9; 2-6 g/kg; p.o.; daily, for 5 d) is a recovery in feces of Sprague-Dawley rats and can efficient uptake and removal of potassium ions.Animal Model:Sprague-Dawley rats
Dosage:2, 4, and 6 g/kg
Administration:Oral administration; daily, for 5 days
Result:Had 99% fecal recovery in rats.Uptake and removal of potassium ions in a dose-dependent manner.
体外研究：
Sodium zirconium cyclosilicate (ZS-9) 是一种无机阳离子交换晶体化合物，具有高选择性截留单价阳离子的能力，特别是过量的 K+ 和铵离子。Sodium zirconium cyclosilicate 对二价离子 Ca2+ 和 Mg2+ 的交换容量均低于 0.05 mEq/g，对 K+ 选择性超过 Ca2+ 或 Mg2+ >25 倍。溶解注意事项：Sodium zirconium cyclosilicate 通常配置悬浮液作为储备液，分装储存在 -80℃。
Sodium zirconium cyclosilicate is an orally administered, non-absorbed, novel, inorganic microporous zirconium silicate compound, is a highly selective cation exchanger that selectively removes excess K+ in vivo. Sodium zirconium cyclosilicate can be used in research of chronic kidney disease (CKD).
体内研究：
Sodium zirconium cyclosilicate (ZS-9; 2-6 g/kg; p.o.; daily, for 5 d) is a recovery in feces of Sprague-Dawley rats and can efficient uptake and removal of potassium ions.Animal Model:Sprague-Dawley rats
Dosage:2, 4, and 6 g/kg
Administration:Oral administration; daily, for 5 days
Result:Had 99% fecal recovery in rats.Uptake and removal of potassium ions in a dose-dependent manner.
体外研究：
Sodium zirconium cyclosilicate (ZS-9) 是一种无机阳离子交换晶体化合物，具有高选择性截留单价阳离子的能力，特别是过量的 K+ 和铵离子。Sodium zirconium cyclosilicate 对二价离子 Ca2+ 和 Mg2+ 的交换容量均低于 0.05 mEq/g，对 K+ 选择性超过 Ca2+ 或 Mg2+ >25 倍。溶解注意事项：Sodium zirconium cyclosilicate 通常配置悬浮液作为储备液，分装储存在 -80℃。
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