产品
编 号：F208371
分子式：C15H22N2O4
分子量：294.35
分子式：C15H22N2O4
分子量：294.35
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CAS No: 17355-10-1
产品详情
生物活性：
Tyrosylleucine (Tyr-Leu, YL), an orally active dipeptide, exhibits a potent antidepressant-like activity.
体内研究：
Tyrosylleucine (YL), administered orally, intracerebroventricularly, or intraperitoneally exhibits a potent antidepressant-like activity in the forced swim and tail suspension tests in na?ve mice.Animal Model:Male ddY mice (24-27?g)
Dosage:0.1-30?mg/kg, i.p.; 0.1-1.0 nmol/mouse, i.c.v.; 30-100?mg/kg, p.o.
Administration:Administered orally, intracerebroventricularly, or intraperitoneally
Result:Decreased immobility time after intraperitoneal (1-30?mg/kg) and intracerebroventricular (0.3-1 nmol/mouse) administrations in the FST. Exhibited a potent antidepressant-like activity in the forced swim and tail suspension tests in na?ve mice.
Tyrosylleucine (Tyr-Leu, YL), an orally active dipeptide, exhibits a potent antidepressant-like activity.
体内研究：
Tyrosylleucine (YL), administered orally, intracerebroventricularly, or intraperitoneally exhibits a potent antidepressant-like activity in the forced swim and tail suspension tests in na?ve mice.Animal Model:Male ddY mice (24-27?g)
Dosage:0.1-30?mg/kg, i.p.; 0.1-1.0 nmol/mouse, i.c.v.; 30-100?mg/kg, p.o.
Administration:Administered orally, intracerebroventricularly, or intraperitoneally
Result:Decreased immobility time after intraperitoneal (1-30?mg/kg) and intracerebroventricular (0.3-1 nmol/mouse) administrations in the FST. Exhibited a potent antidepressant-like activity in the forced swim and tail suspension tests in na?ve mice.
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