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编 号:F225067
分子式:C21H17F3N3NaO5
分子量:471.36
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1mg
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5mg
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10mg
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50mg
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100mg
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生物活性:
Bictegravir sodium is a potent inhibitor of HIV-1 integrase, with an IC50 of 7.5 nM. Bictegravir sodium exhibits potent and selective anti-HIV activity and low cytotoxicity.

体外研究:
Bictegravir sodium potently inhibits HIV-1 replication in both MT-2 and MT-4 cells with EC50s of 1.5 and 2.4 nM, respectively, and selectivity indices (50% cytotoxic concentration [CC50]/EC50) of ~6,800 in MT-2 cells and ~1,500 in MT-4 cells.
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