产品
编 号：F231315
分子式：C23H27N3O2
分子量：377.48
分子式：C23H27N3O2
分子量：377.48
产品类型
规格
价格
是否有货
1mg
询价
询价
5mg
询价
询价
10mg
询价
询价
25mg
询价
询价
50mg
询价
询价
结构图
CAS No: 185259-85-2
产品详情
生物活性：
GR-46611 is a 5-HT1D receptor agonist. GR-46611 can be used in the research of bladder hyperactivity, leukemia.
体内研究：
GR-46611 (1 mg/kg, i.p. ) significantly improves survival of Dravet syndrome (DS) mice.GR-46611 (0.03-300 μg/kg, i.v.) increases threshold volume, bladder capacity, and residual volume in chronic spinal cord injury (SCI) cats.GR46611 (3-30 mg/kg, s.c.) causes a dose-related decrease in rectal temperature in the adult guinea-pig.Animal Model:Dravet syndrome (DS) mice
Dosage:0.01, 0.1 and 1 mg/kg
Administration:Intraperitoneal injection (i.p.)
Result:Improved survival relative to vehicle treated controls with 89% surviving rate.
体外研究：
GR-46611 (1 μM, 48 h) induces CEM cell proliferation.
GR-46611 is a 5-HT1D receptor agonist. GR-46611 can be used in the research of bladder hyperactivity, leukemia.
体内研究：
GR-46611 (1 mg/kg, i.p. ) significantly improves survival of Dravet syndrome (DS) mice.GR-46611 (0.03-300 μg/kg, i.v.) increases threshold volume, bladder capacity, and residual volume in chronic spinal cord injury (SCI) cats.GR46611 (3-30 mg/kg, s.c.) causes a dose-related decrease in rectal temperature in the adult guinea-pig.Animal Model:Dravet syndrome (DS) mice
Dosage:0.01, 0.1 and 1 mg/kg
Administration:Intraperitoneal injection (i.p.)
Result:Improved survival relative to vehicle treated controls with 89% surviving rate.
体外研究：
GR-46611 (1 μM, 48 h) induces CEM cell proliferation.
产品资料
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