产品
编 号:F232362
分子式:C12H19NO4
分子量:241.28
产品类型
结构图
CAS No: 186268-78-0
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生物活性:
GPI-1485 (GM1485), a nonimmunosuppressive immunophilin ligand, promotes neurofunctional improvement and neural regeneration following stroke.
体内研究:
GPI-1485 (GM1485; 5 mg/kg; intraperitoneal injection; 6-week period of daily) improves long-term neurological recovery in rats.Animal Model:Adult male Wistar rats, weighing 250-300 g
Dosage:5 mg/kg
Administration:Intraperitoneal injection; daily; for a total of 42 days
Result:Administration improved neurological function and is consistent with an upregulation of endogenous neurogenesis following stroke in rats.
体外研究:
GPI-1485 (GM1485; 100 μM) induces cellular reprogramming and neural cell induction in normal human dermal fibroblasts (NHDF).