产品
编 号:F232566
分子式:C21H22ClN3O3
分子量:399.87
产品类型
10mM*1mL in DMSO
825
In-stock
结构图
CAS No: 186392-40-5
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产品详情
生物活性:
CP-91149 is a GP (glycogen phosphorylase) inhibitor. CP-91149 promotes glycogen resynthesis, but not its overaccumulation. CP-91149 has the potential for Type II (insulin-dependent) diabetes study.
体外研究:
CP-91149 treatment decreases muscle GP activity by converting the phosphorylated AMP-independent α form into the dephosphorylated AMP-dependent b form and inhibiting GP α activity and AMP-mediated GP b activation.CP-91149 (10, 30, 50 μM) inhibits brain GP and causes glycogen accumulation in A549 cells.