产品
编 号：F240477
分子式：C22H24N2O3
分子量：364.44
分子式：C22H24N2O3
分子量：364.44
产品类型
规格
价格
是否有货
5mg
询价
询价
10mg
询价
询价
结构图
CAS No: 1933533-18-6
产品详情
生物活性：
SPT-IN-1 (compound 1) is an orally active and potent SPT (serine palmitoyl transferase) inhibitor, with an IC50 of 5.19 nM for hSPT1. SPT-IN-1 can be used for type 2 diabetes and dyslipidemia research.
体内研究：
SPT-IN-1 (compound 1) (Sprague Dawley rats, 0-60 mg/kg, Orally, twice daily for 7 days) dose-dependently reduces plasma ceramides, reduces triglycerides and raises HDL in cholesterol/cholic acid fed rats.
体外研究：
SPT-IN-1 (compound 1) exhibits a dose-dependent inhibition of C14-serine incorporation into ceramide in MCF-7 cells, with EC50 of 0.98 μM.
SPT-IN-1 (compound 1) is an orally active and potent SPT (serine palmitoyl transferase) inhibitor, with an IC50 of 5.19 nM for hSPT1. SPT-IN-1 can be used for type 2 diabetes and dyslipidemia research.
体内研究：
SPT-IN-1 (compound 1) (Sprague Dawley rats, 0-60 mg/kg, Orally, twice daily for 7 days) dose-dependently reduces plasma ceramides, reduces triglycerides and raises HDL in cholesterol/cholic acid fed rats.
体外研究：
SPT-IN-1 (compound 1) exhibits a dose-dependent inhibition of C14-serine incorporation into ceramide in MCF-7 cells, with EC50 of 0.98 μM.
产品资料
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