产品
编 号：F242653
分子式：C25H33N3O4S
分子量：471.61
分子式：C25H33N3O4S
分子量：471.61
产品类型
规格
价格
是否有货
结构图
CAS No: 1952239-59-6
产品详情
生物活性：
CD12681 (compound 14) is a potent and selective RORγ inverse agonist with IC50 of 19 nM and 10 nM for RORγ GAL4 and CD4-IL-17 cells, respectively. CD12681 decreases the IL-17 inflammatory cell recruitment. CD12681 has the potential for the research of psoriasis.
体外研究：
CD12681 (compound 14) shows inhibition with IC50s of 44, >25, 9 μM for CYP 3A4, CYP 2D6, hERG, respectively.
CD12681 (compound 14) is a potent and selective RORγ inverse agonist with IC50 of 19 nM and 10 nM for RORγ GAL4 and CD4-IL-17 cells, respectively. CD12681 decreases the IL-17 inflammatory cell recruitment. CD12681 has the potential for the research of psoriasis.
体外研究：
CD12681 (compound 14) shows inhibition with IC50s of 44, >25, 9 μM for CYP 3A4, CYP 2D6, hERG, respectively.
产品资料
Copyright©2015-2024 沪ICP备2022026524号-1
沪公网安备