产品
编 号:F243821
分子式:C43H45ClN8O9S
分子量:885.38
产品类型
结构图
CAS No: 1957234-83-1
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产品详情
生物活性:
dBET23 is a highly effective and selective PROTAC BRD4 degrader with a DC50/5h of ~ 50 nM for BRD4BD1 protein.
体外研究:
dBET23 occupies the canonical binding sites on CRBN and BRD4BD1 for thalidomide and JQ1, respectively.