产品
编 号:F247115
分子式:C13H17N5O2
分子量:275.31
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10mM*1mL in DMSO
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1mg
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5mg
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10mg
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50mg
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100mg
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生物活性:
SJ572403 (SJ403) is a p27Kip1 inhibitor. SJ572403 has high specificity for specific regions within the D2 subdomain of p27-KID with a Kd value of 2.2 mM. SJ572403 can be used for the research of diseases associated with intrinsically disordered proteins (IDPs).

体外研究:
SJ572403 (SJ403) (3 mM) shows specific interactions with specific regions within the D2 subdomain of p27-KID with a Kd value of 2.2 mM.SJ572403 (0-3 mM) modulates p27's Cdk regulatory.SJ572403 (10 μM-3 mM) displaces p27-D2 from Cdk2/cyclin A and partially restores Cdk2 kinase activity.
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