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编 号:F250250
分子式:C15H20O8
分子量:328.31
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生物活性:
Paeonoside is a bioactive compound identified in P. suffruticosa that promotes wound healing and migration in osteoblast differentiation. Paeonoside has also been reported to have some antidiabetic activity and may prevent sepsis-induced lethality.

体外研究:
Paeonoside (PASI) (0.1-100 μM, 24 h) has no cytotoxic effect on pro-osteoblasts of MC3T3-E1 cells. Paeonoside (PASI) (1-30 μM, 24 h) can significantly restore wound areas and promote cell migration in a dose-dependent manner during the induction of preosteoblast of MC3T3-E1 cells differentiation using osteogenic supplement (OS) medium. In parallel, PASI promotes alkaline phosphatase (ALP) staining and its activity in a dose-dependent manner.
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