产品
编 号:F252353
分子式:C27H44N8O8
分子量:608.69
产品类型
结构图
CAS No: 2055024-65-0
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产品详情
生物活性:
Azido-PEG3-Val-Cit-PAB-OH is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Azido-PEG3-Val-Cit-PAB-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
体外研究:
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.