产品
编 号:F269974
分子式:C27H32F3IN2O2
分子量:600.45
产品类型
结构图
CAS No: 2101317-21-7
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产品详情
生物活性:
S-Gboxin, a functional analogue of Gboxin, inhibits growth of mouse and human glioblastoma (GBM) with an IC50 of 470 nM. Antitumour activity.
体内研究:
S-Gboxin retains excellent metabolic stability, enhanced plasma stability, and PK-propertiessuitable for in vivo studies. S-Gboxin (10 mg/kg/day; intraperitoneally) inhibits glioblastoma (GBM) growth in vivo.Animal Model:Female nude mice (6 to 9 weeks)
Dosage:10 mg/kg/day
Administration:Administered intraperitoneally; daily; 3 or 14 days
Result:Resulted in significant attenuation of growth and decreased cellular density compared to controls.