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编 号:F273764
分子式:C39H45N3O8S
分子量:715.85
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生物活性:
ROS tracer precursor is the precursor of [18F]ROStrace for the synthesis of ROStrace, which can be used for disease diagnosis.

体内研究:
[18F]ROStrace is a radiotracer for imaging superoxide in vivo with positron emission tomography (PET), in an LPS model of neuroinflammation.[18F]ROStrace is found to rapidly cross the blood-brain barrier (BBB) and is trapped in the brain of LPS-treated animals. [18F]ox-ROStrace, the oxidized form of [18F]ROStrace, does not cross the BBB. [18F]ROStrace is a suitable radiotracer for imaging superoxide levels in the central nervous system with PET.
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