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编 号:F275604
分子式:C16H18N2
分子量:238.33
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生物活性:
Metapramine (19560 RP) is an antidepressant agent, belonging to the class of tricyclic compounds. Metapramine inhibits norepinephrine reuptake, without affecting the reuptake of serotonin or dopamine. Metapramine is a low-affinity antagonist of the N-methyl-D-aspartic acid (NMDA) receptor complex channel.

体内研究:
Metapramine (19560 RP) (0-20 mg/kg; i.p.) shows analgesic effects in mice.Animal Model:Male Swiss albino mice
Dosage:0-20 mg/kg
Administration:Intraperitoneal injection
Result:Increased jump latency, threshold voltage, reduction in writhes, and tail flick latency in a dose-dependent manner.
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