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编 号:F277023
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CAS No: 219649-07-7
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生物活性:
Labetuzumab is a humanised anti-carcinoembryonic antigen (CEA) monoclonal antibody that inhibits tumour growth and sensitises human medullary thyroid cancer xenografts to Dacarbazine chemotherapy.
体内研究:
Labetuzumab (0.5 mg/rat; i.v.; single) inhibits tumor growth in vivo.Animal Model:Female nu/nu mice (6 to 8-week-old; inject TT cells).
Dosage:0.5 mg/rat
Administration:Intravenous injection; single (1 day post-tumor cell injection)
Result:Significantly delaied growth of tumor, and led to 64%-70% inhibition of tumor size between days 32 and 60.