产品
编 号：F279860
分子式：C23H25N9S
分子量：459.57
分子式：C23H25N9S
分子量：459.57
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规格
价格
是否有货
结构图
CAS No: 2227019-45-4
产品详情
生物活性：
Aurora inhibitor 1 is a potent Aurora inhibitor with an IC50 of ≤ 4 nM and ≤13 nM for Aurora A and Aurora B kinase, respectively.
体内研究：
Aurora inhibitor 1 (Compound 16) exhibits good drug exposure levels across species upon oral dosing, and shows excellent in vivo efficacy in a mouse xenograft tumor model when dosed orally.
体外研究：
Aurora inhibitor 1 (Compound 16) exhibits Kd values of 0.01?nM for both Aurora A and Aurora B kinase.
Aurora inhibitor 1 is a potent Aurora inhibitor with an IC50 of ≤ 4 nM and ≤13 nM for Aurora A and Aurora B kinase, respectively.
体内研究：
Aurora inhibitor 1 (Compound 16) exhibits good drug exposure levels across species upon oral dosing, and shows excellent in vivo efficacy in a mouse xenograft tumor model when dosed orally.
体外研究：
Aurora inhibitor 1 (Compound 16) exhibits Kd values of 0.01?nM for both Aurora A and Aurora B kinase.
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