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编 号:F280884
分子式:C18H23FN2O6
分子量:382.38
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10mM*1mL in DMSO
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1mg
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5mg
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10mg
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50mg
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生物活性:
EP1013 (F1013) is a broad-spectrum caspase selective inhibitor, used in the research of type 1 diabetes.

体内研究:
EP1013 (1, 3, 10 mg/kg) significantly improves marginal islet mass function. Two animals in the 10 mg/kg EP1013 treatment group exhibit primary islet graft nonfunction, but the diabetes reversalrate for this group is not significantly different from the 3 mg/kg EP1013, 1 mg/kg EP1013, or 10 mg/kg zVAD groups. EP1013 therapy enhances functional syngeneic islet mass and promotes longevity of islet graft function.
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