产品
编 号:F280884
分子式:C18H23FN2O6
分子量:382.38
产品类型
结构图
CAS No: 223568-55-6
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产品详情
生物活性:
EP1013 (F1013) is a broad-spectrum caspase selective inhibitor, used in the research of type 1 diabetes.
体内研究:
EP1013 (1, 3, 10 mg/kg) significantly improves marginal islet mass function. Two animals in the 10 mg/kg EP1013 treatment group exhibit primary islet graft nonfunction, but the diabetes reversalrate for this group is not significantly different from the 3 mg/kg EP1013, 1 mg/kg EP1013, or 10 mg/kg zVAD groups. EP1013 therapy enhances functional syngeneic islet mass and promotes longevity of islet graft function.