产品
编 号:F281136
分子式:C24H47NO7
分子量:461.63
产品类型
结构图
CAS No: 2238-90-6
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产品详情
生物活性:
Psychosine (Galactosylsphingosine), a substrate of the galactocerebrosidase (GALC) enzyme, is a potential biomarker for Krabbe disease. Psychosine is a highly cytotoxic lipid, capable of inducing cell death in a wide variety of cell types including, most relevantly to globoid cell leukodystrophy (GLD), oligodendrocytes. Psychosine causes cell death at least in part via apoptosis. Psychosine also is an inhibitor of PKC.
体外研究:
Psychosine 是 GALC 酶的底物,有望帮助诊断和随访通过新生儿筛查 (NBS) 确定的高危婴儿。Psychosine 具有多效性,包括多种细胞通路的功能障碍。