产品
编 号:F281601
分子式:C22H27ClN8O3S
分子量:519.02
产品类型
结构图
CAS No: 2244775-31-1
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生物活性:
F-1 is a potent ALK and ROS1 dual inhibitor, suppresses phospho-ALK and its relative downstream signaling pathways, with IC50s of 2.1 nM, 2.3 nM, 1.3 nM and 3.9 nM for ALKWT, ROS1WT, ALKL1196M and ALKG1202R, respectively.