产品
编 号:F286374
分子式:C25H29N5O4S
分子量:495.59
产品类型
结构图
CAS No: 2355377-13-6
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产品详情
生物活性:
DDO-5936 is a potent and specific Hsp90-Cdc37 PPI inhibitor. DDO-5936 can be used for the research of colorectal cancer.
体内研究:
DDO-5936 (0~80 mg/kg; p.o.) shows effect at the high dose group.DDO-5936 is well tolerated for the absence of serious weight loss. DDO-5936 high dose groups show that tumor cells in the xenografts decreased significantly. DDO-5936 shows limited oral efficiency.Animal Model:Mice
Dosage:0~80 mg/kg
Administration:P.o.
Result:Showed a moderate effect at the high dose group.
体外研究:
DDO-5936 is a Hsp90-Cdc37 PPI inhibitor with potency and specificity through binding to a critical site on Hsp90 involving Glu47.