产品
编 号:F286890
分子式:C17H27N3O7S
分子量:417.48
产品类型
结构图
CAS No: 236754-49-7
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产品详情
生物活性:
Azide-PEG5-Tos is a cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Azide-PEG5-Tos is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
体外研究:
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.