产品
编 号:F287255
分子式:C20H16ClN5O2
分子量:393.83
产品类型
结构图
CAS No: 2376577-06-7
联系客服
产品详情
生物活性:
M2N12 is a potent and highly selective cell division cycle 25C protein phosphatase (Cdc25C) inhibitor with an IC50 value of 0.09 ?μM. M2N12 also has promising activity against Cdc25A and Cdc25B with IC50 values of ?0.53? μM and 1.39 μM, respectively. M2N12 has anti-tumor activity and can be used for cancer research.
体外研究:
M2N12 (0-20 μM; 72 hours) has cytotoxic activity against five tumor cell lines and a normal cell line including A-549, MDA-MB-231, KB, KB-VIN, MCF-7 and HBE (IC50=3.92 μM, 4.63 μM, 5.05 μM, 6.81 μM, 4.71 μM and 6.00 μM, respectively).