产品
编 号：F287285
分子式：C24H17F6NO5S
分子量：545.45
分子式：C24H17F6NO5S
分子量：545.45
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CAS No: 2377378-89-5
产品详情
生物活性：
RORγt agonist 1 (compound 14) is a potent, orally bioavailable RORγt agonist with an EC50 of 20.8?nM. RORγt agonist 1 showes high metabolic stability, improved aqueous solubility and excellent mouse PK profile. RORγt agonist 1 is a potential candidate of RORγt agonist for cancer immunotherapy.
体内研究：
RORγt agonist 1 shows high metabolic stability (t1/2?=?113?min) in mouse liver microsome and has improved aqueous solubility at pH 7.4.
RORγt agonist 1 (compound 14) is a potent, orally bioavailable RORγt agonist with an EC50 of 20.8?nM. RORγt agonist 1 showes high metabolic stability, improved aqueous solubility and excellent mouse PK profile. RORγt agonist 1 is a potential candidate of RORγt agonist for cancer immunotherapy.
体内研究：
RORγt agonist 1 shows high metabolic stability (t1/2?=?113?min) in mouse liver microsome and has improved aqueous solubility at pH 7.4.
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