产品
编 号：F290726
分子式：C11H15N5O3S
分子量：297.33
分子式：C11H15N5O3S
分子量：297.33
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
25mg
400
In-stock
50mg
680
In-stock
100mg
1200
In-stock
结构图
CAS No: 2457-80-9
产品详情
生物活性：
5'-Methylthioadenosine (5'-(Methylthio)-5'-deoxyadenosine) is a nucleoside generated from S-adenosylmethionine (SAM) during polyamine synthesis. 5'-Methylthioadenosine suppresses tumors by inhibiting tumor cell proliferation, invasion, and the induction of apoptosis while controlling the inflammatory micro-environments of tumor tissue. 5'-Methylthioadenosine and its associated materials have striking regulatory effects on tumorigenesis.
体内研究：
2FA (2'-氟腺嘌呤)+MTA (5'-Methylthioadenosine) 组合 (100 mg/kg MTA；20 mg/kg 2FA) 抑制四种不同 MTAP小鼠异种移植模型中的人肿瘤细胞系。
体外研究：
5'-Methylthioadenosine 对 MTAP+ 细胞的保护作用明显优于 MTAP细胞免受 6TG (6'-硫鸟嘌呤) 的影响毒性。
5'-Methylthioadenosine (5'-(Methylthio)-5'-deoxyadenosine) is a nucleoside generated from S-adenosylmethionine (SAM) during polyamine synthesis. 5'-Methylthioadenosine suppresses tumors by inhibiting tumor cell proliferation, invasion, and the induction of apoptosis while controlling the inflammatory micro-environments of tumor tissue. 5'-Methylthioadenosine and its associated materials have striking regulatory effects on tumorigenesis.
体内研究：
2FA (2'-氟腺嘌呤)+MTA (5'-Methylthioadenosine) 组合 (100 mg/kg MTA；20 mg/kg 2FA) 抑制四种不同 MTAP小鼠异种移植模型中的人肿瘤细胞系。
体外研究：
5'-Methylthioadenosine 对 MTAP+ 细胞的保护作用明显优于 MTAP细胞免受 6TG (6'-硫鸟嘌呤) 的影响毒性。
产品资料
Copyright©2015-2024 沪ICP备2022026524号-1
沪公网安备