产品
编 号：F290747
分子式：C11H16N4O4
分子量：268.27
分子式：C11H16N4O4
分子量：268.27
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
5mg
132
In-stock
10mg
211
In-stock
25mg
400
In-stock
50mg
640
In-stock
100mg
1040
In-stock
结构图
CAS No: 24584-09-6
产品详情
生物活性：
Dexrazoxane (ICRF-187) is a cardioprotective agent.Target: OthersDexrazoxane is a cardioprotective agent. Dexrazoxane is a derivative of EDTA, dexrazoxane chelates iron and thus reduces the number of metal ions complexed with anthracycline and, consequently, decrease the formation of superoxide radicals. The exact chelation mechanism is unknown, but it has be postulated that dexrazoxane can be converted into ring-opened form intracellularly and interfere with iron-mediated free radical generation that is in part thought to be responsible for anthryacycline induced cadiomyopathy. It was speculated that dexrazoxane could be used for further investigation to synthesize new antimalarial drugs [1, 2].
Dexrazoxane (ICRF-187) is a cardioprotective agent.Target: OthersDexrazoxane is a cardioprotective agent. Dexrazoxane is a derivative of EDTA, dexrazoxane chelates iron and thus reduces the number of metal ions complexed with anthracycline and, consequently, decrease the formation of superoxide radicals. The exact chelation mechanism is unknown, but it has be postulated that dexrazoxane can be converted into ring-opened form intracellularly and interfere with iron-mediated free radical generation that is in part thought to be responsible for anthryacycline induced cadiomyopathy. It was speculated that dexrazoxane could be used for further investigation to synthesize new antimalarial drugs [1, 2].
产品资料
Copyright©2015-2024 沪ICP备2022026524号-1
沪公网安备