产品
编 号：F296597
分子式：C16H27N3O4
分子量：325.4
分子式：C16H27N3O4
分子量：325.4
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CAS No: 26001-32-1
产品详情
生物活性：
H-Ile-Pro-Pro-OH, a milk-derived peptide, inhibits angiotensin-converting enzyme (ACE) with an IC50 of 5 μM. Antihypertensive tripeptides.
体内研究：
Ile-Pro-Pro (IPP; 30 mg/kg per day; 0.3 g/L) attenuates arterial dysfunction in L-NAME-treated ratsIle-Pro-Pro decreases blood pressure in spontaneously hypertensive rats (SHR) .Ile-Pro-Pro attenuates the development of atherosclerosis in apolipoprotein E-deficient(apoE(-/-)) mice.
体外研究：
Ile-Pro-Pro (IPP; 1 nM, 0.1 μM, and 10 μM) increases nitric oxide (NO) production in human umbilical vein endothelial cells (HUVECs).
H-Ile-Pro-Pro-OH, a milk-derived peptide, inhibits angiotensin-converting enzyme (ACE) with an IC50 of 5 μM. Antihypertensive tripeptides.
体内研究：
Ile-Pro-Pro (IPP; 30 mg/kg per day; 0.3 g/L) attenuates arterial dysfunction in L-NAME-treated ratsIle-Pro-Pro decreases blood pressure in spontaneously hypertensive rats (SHR) .Ile-Pro-Pro attenuates the development of atherosclerosis in apolipoprotein E-deficient(apoE(-/-)) mice.
体外研究：
Ile-Pro-Pro (IPP; 1 nM, 0.1 μM, and 10 μM) increases nitric oxide (NO) production in human umbilical vein endothelial cells (HUVECs).
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