产品
编 号：F297116
分子式：C11H15N2O4PS
分子量：302.29
分子式：C11H15N2O4PS
分子量：302.29
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
2mg
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5mg
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10mg
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50mg
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结构图
CAS No: 261365-11-1
产品详情
生物活性：
MB05032 is a special and efficacious gluconeogenesis inhibitor targeted the AMP binding site of fructose 1,6-bisphosphatase (FBPase) with an IC50 value of 16 nM.
体内研究：
MB06322 (3/6-300 mg/kg (年轻/老年 Zucker 糖尿病肥胖 (ZDF) 大鼠)；口服；一次) 导致患有轻度糖尿病的年轻 ZDF 大鼠和患有明显糖尿病的老年 ZDF 大鼠剂量依赖性葡萄糖降低。Animal Model:ZDF rats (8- to 9-week-old (mild diabetes) and 12- to 13-week-old (overt diabetes))
Dosage:3, 6, 10, 30, 300 mg/kg (young ZDF rats); 6, 10, 30, 300 mg/kg (aged ZDF rats)
Administration:Oral administration; once
Result:Results in dose-dependent glucose lowering.
MB05032 is a special and efficacious gluconeogenesis inhibitor targeted the AMP binding site of fructose 1,6-bisphosphatase (FBPase) with an IC50 value of 16 nM.
体内研究：
MB06322 (3/6-300 mg/kg (年轻/老年 Zucker 糖尿病肥胖 (ZDF) 大鼠)；口服；一次) 导致患有轻度糖尿病的年轻 ZDF 大鼠和患有明显糖尿病的老年 ZDF 大鼠剂量依赖性葡萄糖降低。Animal Model:ZDF rats (8- to 9-week-old (mild diabetes) and 12- to 13-week-old (overt diabetes))
Dosage:3, 6, 10, 30, 300 mg/kg (young ZDF rats); 6, 10, 30, 300 mg/kg (aged ZDF rats)
Administration:Oral administration; once
Result:Results in dose-dependent glucose lowering.
产品资料
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