产品
编 号:F297418
分子式:C23H36N4O5S
分子量:480.62
产品类型
结构图
CAS No: 261766-73-8
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产品详情
生物活性:
5-HT4 antagonist 1 is a 5-HT4 receptor antagonist with a pKi of 9.6.
体内研究:
5-HT4 antagonist 1 (compound 6b) demonstrates good exposure and prolongs t1/2 in other species, including the mouse (t1/2 7 h), rat (t1/2 12 h) and mini-pig (t1/2 21 h). In Phase I clinical trial, it is found that 5-HT4 antagonist 1 has good oral bioavailability with a steady state plasma t1/2 of >100 h.
体外研究:
5-HT4 antagonist 1 (compound 6b) is a 5-HT4 receptor antagonist with a pKi of 9.6.