产品
编 号：F034944
分子式：C19H22O4
分子量：314.38
分子式：C19H22O4
分子量：314.38
产品类型
规格
价格
是否有货
1mg
询价
询价
5mg
询价
询价
10mg
询价
询价
结构图
CAS No: 109664-02-0
产品详情
生物活性：
Neocryptotanshinone, a fatty diterpenoids from Salvia Miltiorrhiza, inhibits lipopolysaccharide-induced inflammation by suppression of NF-κB and iNOS signaling pathways.
体内研究：
Neocryptotanshinone causes reversals of decreased pain thresholds induced by MSU treatment after 30, 60, and 120 min S. miltiorrhiza Bunge extract treatment (contains single active components).Animal Model:MSU-induced pain model in male ICR mice (weighing 20-25 g)
Dosage:10, 25, 50 or 100 mg/kg
Administration:Oral gavage; for 30, 60, 120 min
Result:Inhibited inflammatory symptoms and nociceptive behaviors in a dose-dependent manner.
体外研究：
Neocryptotanshinone exhibits anti-inflammatory effect by suppression of NF-κB and iNOS signaling pathways.Neocryptotanshinone (10 μM and 20 μM, 24 h) inhibits LPS-induced iNOS protein expression in RAW264.7 cells.Neocryptotanshinone (20 μM, 24 h) shows no obvious cytotoxic effect towards murine RAW264.7 macrophages.
Neocryptotanshinone, a fatty diterpenoids from Salvia Miltiorrhiza, inhibits lipopolysaccharide-induced inflammation by suppression of NF-κB and iNOS signaling pathways.
体内研究：
Neocryptotanshinone causes reversals of decreased pain thresholds induced by MSU treatment after 30, 60, and 120 min S. miltiorrhiza Bunge extract treatment (contains single active components).Animal Model:MSU-induced pain model in male ICR mice (weighing 20-25 g)
Dosage:10, 25, 50 or 100 mg/kg
Administration:Oral gavage; for 30, 60, 120 min
Result:Inhibited inflammatory symptoms and nociceptive behaviors in a dose-dependent manner.
体外研究：
Neocryptotanshinone exhibits anti-inflammatory effect by suppression of NF-κB and iNOS signaling pathways.Neocryptotanshinone (10 μM and 20 μM, 24 h) inhibits LPS-induced iNOS protein expression in RAW264.7 cells.Neocryptotanshinone (20 μM, 24 h) shows no obvious cytotoxic effect towards murine RAW264.7 macrophages.
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