产品
编 号：F301786
分子式：C24H28O11
分子量：492.47
分子式：C24H28O11
分子量：492.47
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
5mg
400
In-stock
10mg
640
In-stock
20mg
1120
In-stock
结构图
CAS No: 27409-30-9
产品详情
生物活性：
Picroside I is the major ingredient of Picrorhiza scrophulariiflora. Picrorhiza scrophulariiflora is a high value medicinal herb due to rich source of hepatoprotective metabolites, Picroside-I and Picroside-II. Picroside I is a promising agent for the management of asthma. Picroside I reduces the inflammation significantly at its higher dose. Picroside I also downregulates pSTAT6 and GATA3 expressions. Picroside I dose-dependently increases the serum levels of IFN-γ.
体内研究：
Picroside I（20 mg/kg，p.o，12 d）可降低实验性哮喘模型中的 AHR，并降低 OVA 相关 IgE 水平。Animal Model:Ovalbumin (OVA) systematic sensitization BALB/c mice model
Dosage:0.2, 2.0 and 20 mg/kg
Administration:Orally, once daily, from day 20 to day 32
Result:Inhibited allergen-triggered inflammatory cell infiltration.
Picroside I is the major ingredient of Picrorhiza scrophulariiflora. Picrorhiza scrophulariiflora is a high value medicinal herb due to rich source of hepatoprotective metabolites, Picroside-I and Picroside-II. Picroside I is a promising agent for the management of asthma. Picroside I reduces the inflammation significantly at its higher dose. Picroside I also downregulates pSTAT6 and GATA3 expressions. Picroside I dose-dependently increases the serum levels of IFN-γ.
体内研究：
Picroside I（20 mg/kg，p.o，12 d）可降低实验性哮喘模型中的 AHR，并降低 OVA 相关 IgE 水平。Animal Model:Ovalbumin (OVA) systematic sensitization BALB/c mice model
Dosage:0.2, 2.0 and 20 mg/kg
Administration:Orally, once daily, from day 20 to day 32
Result:Inhibited allergen-triggered inflammatory cell infiltration.
产品资料
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