产品
编 号:F303098
分子式:C17H26O12
分子量:422.38
产品类型
结构图
CAS No: 27856-54-8
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产品详情
生物活性:
Lamiide, an orally active iridoid compound, can be found in Bouchea fluminensis leaves. Lamiide exhibits anti-inflammatory and anti-lipoperoxidative activity.
体内研究:
Lamiide (12.5-100 mg/kg; p.o. 30 min before Carrageenin injection) dose-dependently reduces Carrageenin-induced edema.Animal Model:Female Wistar rats (8-weeks old, 150-200 g) were injected with Carrageenin in the subplantar aponeurosis of the right hind paw
Dosage:12.5, 25, 50, 100 mg/kg
Administration:P.o. 30 min before Carrageenin injection
Result:Reduced Carrageenin-induced edema, with an ED50 of 62.3 mg/kg.
体外研究:
Lamiide inhibits rat-brain phospholipid peroxidation, with an IC50 of 0.92 mM.