产品
编 号:F307404
分子式:C16H13ClN2S
分子量:300.81
产品类型
结构图
CAS No: 2898-13-7
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产品详情
生物活性:
Sulazepam, a benzodiazepine, is a selective ovarian cancer G protein-coupled receptor (OGR1) agonist. Sulazepam has anticonvulsive action and has the potential for airway hyperresponsiveness (AHR) research.
体内研究:
Sulazepam (3.2 mg/kg in 25 μL via intranasal route ~30 min before HDM challenge; 5 days a week for three consecutive weeks) inhibits the development of airway hyperresponsiveness (AHR) in Male and female wild-type C57BL/6 mice (8-10 wk old), but not in age-matched OGR1KO mice (C57BL/6 background) with house dust mite (HDM) allergen (25 μg; intranasally).