产品
编 号：F308137
分子式：C15H25NO3
分子量：267.36
分子式：C15H25NO3
分子量：267.36
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CAS No: 2922-20-5
产品详情
生物活性：
Butaxamine (Butoxamin) is a potent, selective and orally active β2-adrenoceptor antagonist. Butaxamine shows antiosteoporotic activity.
体内研究：
Butaxamine (0.1, 1, 10 mg/kg; p.o.; once daily for 12 weeks) 增加大鼠的骨量指数以及强度和韧性的生物力学参数。Animal Model:Seven-week-old male SHR/Izm and WKY/Izm rats
Dosage:0.1, 1, 10 mg/kg
Administration:P.o.; once daily for 12 weeks
Result:Prevented a decrease in bone mass and an increase in biomechanical fragility developing in SHR, suppressed both a decrease in bone formation and an increase in bone resorption in SHR.
Butaxamine (Butoxamin) is a potent, selective and orally active β2-adrenoceptor antagonist. Butaxamine shows antiosteoporotic activity.
体内研究：
Butaxamine (0.1, 1, 10 mg/kg; p.o.; once daily for 12 weeks) 增加大鼠的骨量指数以及强度和韧性的生物力学参数。Animal Model:Seven-week-old male SHR/Izm and WKY/Izm rats
Dosage:0.1, 1, 10 mg/kg
Administration:P.o.; once daily for 12 weeks
Result:Prevented a decrease in bone mass and an increase in biomechanical fragility developing in SHR, suppressed both a decrease in bone formation and an increase in bone resorption in SHR.
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