产品
编 号:F309717
分子式:C15H29NO2S
分子量:287.46
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10mM*1mL in DMSO
825
In-stock
5mg
750
In-stock
10mg
1275
In-stock
25mg
2700
In-stock
50mg
4500
In-stock
100mg
7500
In-stock
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生物活性:
CAY10444 (BML-241) is a sphingosine-1-phosphate 3 (S1P3) antagonist. CAY10444 inhibits by 37% S1P-induced increases in Ca2+ in HeLa cells expressing S1P3 receptors.

体外研究:
BML-241 inhibits increases in intracellular Ca2+ concentration via P2 receptor or α1A-adrenoceptor stimulation and α1A-adrenoceptor-mediated contraction of rat mesenteric artery, while it does not affect S1P3-mediated decrease of Forskolin-induced cyclic AMP accumulation.
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