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编 号:F313363
分子式:C10F18
分子量:462.08
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生物活性:
Perfluorodecalin liquids are largrly used in vitreoretinal surgery. Perfluorodecalin with tamponade lasting more than two days is detrimental to the retina in the case of rabbit. Perfluorodecalin can be used for the research of giant retinal tears. Perfluorodecalin is a non-toxic, non-flammable, thermally stable, non-bio-accumulating O2-carrier and used as artificial blood. Perfluorodecalin enhances bone regeneration and cell viability.

体内研究:
Perfluorodecalin (1.1-1.5 ml/eye) 会引起白化兔子的视网膜损伤和炎症。Animal Model:Albino rabbits
Dosage:1.1-1.5 ml for each eye
Administration:injection into vitreous cavity
Result:Induced appearance of foam cells, preretinal membranes, and the interface necrosis.

体外研究:
Perfluorodecalin 可延长细胞在厌氧环境中的存活时间,增强骨水泥的放射性不透性、可注射性、内聚力和骨再生活性。Perfluorodecalin (10% v/v) 可改善封装胰岛移植过程中的缺氧情况并提高细胞活力。
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