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编 号:F313629
分子式:C15H22N2O4
分子量:294.35
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10mM*1mL in DMSO
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100mg
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500mg
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生物活性:
Troxipide is an orally active defensive factor-enhancing therapeutic agent for gastritis and gastric ulcer (GU). Troxipide is a non-antisecretory gastro protective agent with antiulcer, anti-inflammatory and mucus-secreting properties.

体内研究:
Troxipide (40 mg/kg; iv) significantly alleviates gastric ulcer (GU). Troxipide (40 mg/kg; iv) has a T1/2 of 210 min and 428.73 min for NCG and GUG rat, respectively. Animal Model:Normal control group (NCG) and gastric ulcer group (GUG) rat (5% acetic acid 10 mL/kg/day)
Dosage:10, 20, 40, 60 mg/kg
Administration:Oral; daily; 2 weeks
Result:The levels of these cytokines (IL-17, IL-6, TNF-α, IFN-γ and AP-1) were significantly reduced, suggesting that GU was significantly alleviated.
Animal Model:NCG and GUG rat
Dosage:40 mg/kg for iv
Administration:IV
Result:Had a T1/2 of 210 min and 428.73 min for NCG and GUG rat, respectively.

体外研究:
Troxipide exerts inhibitory, therapeutic and preventive effects to specifically those in the stomach by enhancing gastric mucosal blood flow and gastric mucosal defense factors and promoting tissue repair, blood circulation, metabolism and GU repair.
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