产品
编 号:F321324
分子式:C32H46N8O6S2
分子量:702.89
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规格
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10mM*1mL in DMSO
询价
询价
500mg
320
In-stock
1g
400
In-stock
5g
720
In-stock
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生物活性:
Sulbutiamine is a synthetic analogue of vitamin B1 used for the treatment of asthenia.

体外研究:
Sulbutiamine shows neuroprotective effects on hippocampal CA1 pyramidal neurons subjected to oxygen-glucose deprivation. Sulbutiamine enhances electrophysiological properties such as excitatory synaptic transmissions and intrinsic neuronal membrane input resistance in a concentration-dependent manner. Sulbutiamine attenuates apoptotic cell death induced by serum deprivation and stimulates GSH and GST activity in a dose dependent manner. Furthermore, sulbutiamine decreases the expression of cleaved caspase-3 and AIF.
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