产品
编 号:F321591
分子式:C21H27Cl2N3O3S
分子量:472.43
产品类型
结构图
CAS No: 329218-11-3
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生物活性:
Quetiapine sulfoxide dihydrochloride (Quetiapine S-oxide dihydrochloride) is a main metabolite of Quetiapinem. Quetiapine is a second-generation antipsychotic. Quetiapine is a 5-HT receptors agonist and a dopamine receptor antagonist.
体内研究:
The Cmax value (mean±SD) is estimated for Quetiapine sulfoxide (77.3±32.4 ng/mL). The AUClast value is estimated for Quetiapine sulfoxide (1,286±458 ng?h/mL). For Quetiapine sulfoxide, metabolic ratio decreases with time, from 119% on average 2 hours after dosing to 30% on average 72 hours after dosing.