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编 号:F324400
分子式:C41H67NO11
分子量:749.97
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生物活性:
Venturicidin A (Aabomycin A1), from actinomycetes, is a membrane-active natural product inhibitor of ATP synthase. Venturicidin A potentiates the aminoglycoside antibiotic gentamicin against multidrug-resistant clinical isolates of Staphylococcus, Enterococcus, and Pseudomonas aeruginosa. Venturicidin A shows noticeable toxicity toward human embryonic-kidney (HEK)cells with an IC50 of 31 μg/mL.

IC50:
Aminoglycoside

作用靶点:
Aminoglycoside

作用通路:
Aminoglycoside

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