产品
编 号:F327836
分子式:C36H54O10
分子量:646.81
产品类型
结构图
CAS No: 34096-83-8
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产品详情
生物活性:
Glycyrrhetic acid 3-O-β-D-glucuronide, isolated from glycyrrhiza, is an important derivative of glycyrrhizin (GL) with an anti -allergic activity. Glycyrrhetic acid 3-O-β-D-glucuronide (GAMG) shows that β-glucuronidases (β-GUS) are key GAMG-producing enzymes, displaying a high potential to convert GL directly into GAMG.Glycyrrhetic acid 3-O-β-D-glucuronide is valuable as a sweetener.
体外研究:
Glycyrrhetic acid 3-O-β-D-glucuronide can inhibit the release of β-hexosaminidase from RBL-2H3 cells with an IC50?value of 0.28 mM.Glycyrrhetic acid 3-O-β-D-glucuronide (GAMG) significantly reduces the nitrite concentration in a dose-dependent manner with an IC50?value of 120 μM in LPS-induced RAW264.7 cells.