产品
编 号:F330828
分子式:C9H16N4S2
分子量:244.38
产品类型
结构图
CAS No: 34839-70-8
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生物活性:
Metiamide (SK&F 92058) is a histamine H2-receptor antagonist developed from another H2 antagonist, burimamide.
体外研究:
Metiamide (SK&F 92058) is a competitivewith aldehyde substrates and noncompetitive with the Human E3 Aldehyde Dehydrogenase coenzyme, binding to both the free E3 isozyme and the enzyme·coenzyme binary complex with Ki values of 0.92 μM glycolaldehyde as the varied substrate. Data is got as percentage change in GTPase activity induced by metiamide compared with the GTPase activity stimulated by HA (100 μM).