产品
编 号:F334914
分子式:C10H14F2N2O2
分子量:232.23
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1mg
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生物活性:
Seletracetam (Ucb 44212), as an analog of the antiepileptic agent Levetiracetam, is a SV2A modulator for the research of epilepsy.

体外研究:
Seletracetam decreases seizure activity in a number of epilepsy models and binds to the synaptic vesicle protein SV2A.Seletracetam decreases synaptic responses in a time-, frequency- and concentration-dependent manner.Seletracetam modifies rates of presynaptic release.Seletracetam inhibits high-voltage-activated Ca2+ currents and intracellular Ca2+ increase in rat cortical neurons in vitro.
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