产品
编 号:F335847
分子式:C28H33NO7
分子量:495.56
产品类型
结构图
CAS No: 36011-19-5
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产品详情
生物活性:
Cytochalasin E, an epoxide containing Aspergillus-derived fungal metabolite, inhibits angiogenesis and tumor growth. Cytochalasin E is a potent actin depolymerization agent, and it binds and caps the barbed end of actin filaments to prevent actin elongation.
体外研究:
Cytochalasin E prominently inhibits the growth of A549 cells in a dose-dependent manner.Cytochalasin E could induce the up-regulation of autophagy-related protein (LC3-II) and SQSTM1/p62.