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编 号:F336065
分子式:C16H15IN2
分子量:362.21
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10mM*1mL in DMSO
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5mg
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10mg
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25mg
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50mg
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生物活性:
F16 is a potent growth inhibitor of the neu-overexpressing cells and also selectively inhibits proliferation of mammary epithelial as well as a variety of mouse mammary tumor and human breast cancer cell lines. F16 is a mitochondriotoxic compound, and triggers apoptosis or necrosis depending on the genetic background of the target carcinoma cell.

体外研究:
F16 (3 μM; 3 days/7 days) affects growth in several mouse and human cancer cell lines.F16 arrests cell cycle and increases apoptosis in F16-sensitive EpH4-A6 cells.
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