产品
编 号:F336243
分子式:C5H7N5O
分子量:153.14
产品类型
结构图
CAS No: 3614-47-9
联系客服
产品详情
生物活性:
Hydracarbazine is a pyridazine. Hydracarbazine can effectively lower blood pressure, it can be used for the research of high blood pressure.
体内研究:
Hydracarbazine (1-4 mg/kg; i.v. once) induced in the dog, cat and rabbit hypotension by peripheral vasodilation, showed no inhibitory action on vasomotor centers and decreased the hypertensive effects of adrenaline, noradrenaline, 5-hydroxytryptamine, pituitrin, and splanchnic nerve stimulation.Hydracarbazine (15-18 mg/kg; p.o. once daily) prevents the increased blood pressure and heart rate, reduces the renal histol andreduces the hypertensive syndrome with a combination of pempidine in high arterial pressure rats.